SimpliDerm logo
SimpliDerm logo

Better process,better results.1

SimpliDerm’s proprietary, patented and gentle process achieves a sterility assurance level (SAL) of 10-6 with minimal impact to the extracellular matrix and key growth factors. This innovative process results in better handling and performance, healthy inflammatory response and rapid tissue integration.1, 2

Designed for Consistency

Designed to meet the needs of board-certified plastic surgeons, the SimpliDerm process prioritizes consistency in thickness within and between pieces for optimal results.

SimpliDerm diagram
SimpliDerm diagram

Greater tissue strength2

Chart depicting SimpliDerm Suture Retention Strength - Baseline
Chart depicting SimpliDerm Suture Retention Strength - 12 weeks after implantation
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SeeBetter Handling and Performance2

SimpliDerm’s structural composition is similar to native dermis and exhibits greater strength than other hADMs, while maintaining pliability.2

simpliderm_inflam_response_curve

SeeHealthy inflammatory response1

SimpliDerm demonstrated reduced inflammatory and fibrotic responses when compared to AlloDerm RTU in a non-human primate model.1

Chart depicting Pro-inlammatory M1 Macrophage protein (TNFa) levels over 12 weeks for SimpliDerm and AlloDerm RTU

SimpliDerm demonstrated reduced inflammatory response compared to AlloDerm RTU at 4 weeks1

SimpliDerm CD68 Staining image
SimpliDerm
AlloDerm CD68 Staining image
AlloDerm RTU

CD68: marker indicative of inflammation

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Preserved vascular channels (baseline)2

Preserved vascular channels (baseline)
Type IV Collagen

Robust tissue generation at 12 weeks2

Robust tissue generation at 12 weeks
Masson’s Trichrome

SeeRapid Tissue Integration1

SimpliDerm’s innovative process results in minimal impact to the extracellular matrix, which allows for a healthy regenerative response and rapid tissue integration.1,2

By preserving the extracellular matrix, including vascular channels, SimpliDerm facilitates angiogenesis, resulting in new collagen formation, revascularization and host cell repopulation.1,2

By preserving the extracellular matrix, including vascular channels, SimpliDerm facilitates angiogenesis, resulting in new collagen formation, revascularization and host cell repopulation.1,2

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